Inactivated rabies virus particles

Travellers for more than one month to areas with rabies, unless there is reliable access to prompt, safe medical care, or who may be exposed to rabies because of their travel activities, or those who would have limited access to post-exposure medical care. Additional vaccine information: Even if vaccinated, travellers who have sustained an animal bite must obtain urgent medical advice.

Three doses at 0, 7 and 28 days.

1 month before travel

General issues: The single site, intradermal 0.1ml pre-exposure vaccine regimen should not be used in those taking chloroquine for malaria prophylaxis, as this suppresses the response. Specific issues: A confirmed anaphylactic reaction to a previous dose of rabies vaccine, or a confirmed anaphylactic reaction to any component of the vaccine.

Pregnant women and breast-feeding mothers should only be given pre-exposure vaccination if the risk of exposure to rabies is high and rapid access to treatment would be limited.

10 years

Rabies vaccine may cause local reactions such as redness, swelling or pain at the site of injection within 24 to 48 hours of administration. Reactions such as headache, fever, muscle aches, vomiting and nettlerash are rare.

£87 per dose

Inactivated tick borne encephalitis virus.

Travellers particularly for spring and summer travel in warm, forested parts of the at risk areas. Individuals who hike, camp, hunt and undertake fieldwork in endemic forested areas should be vaccinated.

3 doses at 0, 1 and 6 months.

3 months before travel

General issues: A confirmed anaphylactic reaction to a previous dose of TBE vaccine, one of the vaccine components or a confirmed anaphylactic reaction to egg ingestion.

There is no evidence of risk.

3 years

Reported reactions to TBE vaccine are rare. Local reactions such as swelling, pain and redness at the injection site may occur.

£70 per dose

BCG is a Live safe attenuated (weakened form) of Tuberculosis (TB)

BCG vaccination can be given safely to any person of any age, from new born through to old age. This is a once only vaccination in the UK and is highly recommended by the DH to specific groups at higher risk of exposure to TB.

BCG is a single once only injection given by specially trained nurses where there is evidence of a negative tuberculin skin test (mantoux)

3 months before travel

People who have had TB in the past and those with a positive mantoux skin test. This is a live vaccine therefore conditions such as HIV or cancer is contra-indicated. Many people with conditions however can successfully receive BCG with specific nurse management. Those who have received a live vaccination within the last 4 weeks eg MMR or Yellow Fever should delay BCG vaccination by one month. However live vaccines can be given together on the same day.

Although no adverse reports, it is best to avoid BCG in pregnancy. BCG is not contra-indicated in breast feeding therefore can be given after delivery.

25 years – life

A mild local reaction at the BCG injection site is typical. A small blister like response and local reaction is to be expected and this is evidence that the vaccination has been successful, leaving a characteristic small scar.

£70 per dose

A LIVE attenuated (weakened) strain of Yellow Fever virus

Persons aged nine months or older who are travelling to countries that require an International Certificate of Vaccination for entry, or who are travelling to or living in infected areas or countries in the yellow fever endemic zone even if these countries do not require evidence of immunisation on entry. Additional vaccine information: Only a licenced Yellow Fever Centre can provide vaccination. Travellers will require an Internarional Certificate of Vaccination prior to travel to countries where the disease is found. The certificate only becomes valid 10 days after injection. Travellers should factor this in to their plans.

A single injection.

2 weeks before travel

General issues: There is a risk of a rare but serious adverse event, whcih particularly affects infants and older patients. Vaccination should only be provided after a careful assessment of health and travel plans by the clinic. Specific issues: HIV infected patients should not be vaccinated. Patients with thymus disease should not be vaccinated. Those who have received a live vaccination within the last 4 weeks eg MMR or BCG should delay Yellow Fever vaccination by one month. However live vaccines can be given together on the same day.

The vaccine may not be given to pregnant women. In breast feeding, there is no evidence of harm to the baby, but the need for vaccination requires careful assessment.

Life long

Adverse reactions following yellow fever vaccine are typically mild and consist of headache, muscle pain, low grade fever and/or soreness at the injection site. This occurs in about 10 to 30% of recipients.

£85 per dose

There are two types of vaccine available: an injectable and an oral variety. We recommend the use of the injectable variety.

Travellers to countries where typhoid is common, especially if staying with or visiting the local population, or with frequent and/or prolonged exposure to conditions where sanitation and food hygiene are likely to be poor. Additional vaccine information: The vaccine is available in a combined preparation with Hepatitis A.

A single dose by injection.

2 weeks before travel

General issues: Patients who have had a serious reaction (”anaphylaxis”) to a previous dose of this vaccine or its constituents. Specific issues: If you decide to have the oral preparation, you should discuss malaria treatment with the clinician

There is no data available about safety in pregnancy and breast feeding. So, subject to medical assessment, vaccine is not recommended for pregnant or breast feeding women.

3 years

Very few. Temporary tenderness at the site of the injection. Some patients describe temporary headache and nausea.

£56 per dose